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1

Systems Chronotherapeutics

Ballesta, Annabelle, Innominato, Pasquale F., Dallmann, Robert, Rand, David A., Lévi, Francis A., Watts, Stephanie W.

Journal:

Pharmacological Reviews

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

2

Circadian Timing in Cancer Treatments

Lévi, Francis, Okyar, Alper, Dulong, Sandrine, Innominato, Pasquale F., Clairambault, Jean

Journal:

Annual Review of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

3

Chronotherapy and the molecular clock: Clinical implications in oncology

Pasquale F. Innominato, Francis A. Lévi, Georg A. Bjarnason

Journal:

Advanced Drug Delivery Reviews

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

4

The circadian timing system in clinical oncology

Innominato, Pasquale F., Roche, Véronique P., Palesh, Oxana G., Ulusakarya, Ayhan, Spiegel, David, Lévi, Francis A.

Journal:

Annals of Medicine

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

5

The effect of melatonin on sleep and quality of life in patients with advanced breast cancer

Innominato, Pasquale F., Lim, Andrew S., Palesh, Oxana, Clemons, Mark, Trudeau, Maureen, Eisen, Andrea, Wang, Cathy, Kiss, Alex, Pritchard, Kathleen I., Bjarnason, Georg A.

Journal:

Supportive Care in Cancer

Year:

2016

Language:

english

File:

PDF, 819 KB

english, 2016

6

Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why

Stéphanou, Angélique, Fanchon, Eric, Innominato, Pasquale F., Ballesta, Annabelle

Journal:

Acta Biotheoretica

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

7

Optimizing circadian drug infusion schedules towards personalized cancer chronotherapy

Hill, Roger J. W., Innominato, Pasquale F., LÃ©vi, Francis, Ballesta, Annabelle, Gallo, James

Journal:

PLoS Computational Biology

Year:

2020

File:

PDF, 5.26 MB

2020

8

Rescue chemotherapy using multidrug chronomodulated hepatic arterial infusion for patients with heavily pretreated metastatic colorectal cancer

Mohamed Bouchahda, René Adam, Sylvie Giacchetti, Denis Castaing, Catherine Brezault-Bonnet, Dominique Hauteville, Pasquale F. Innominato, Christian Focan, David Machover, Francis Lévi

Journal:

Year:

2009

Language:

english

File:

PDF, 162 KB

english, 2009

9

Expression of neurotrophins and their receptors in pigment cell lesions of the skin

Pasquale F. Innominato, Louis Libbrecht, Joost J. van den Oord

Journal:

The Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 325 KB

english, 2001

10

AcquiredKRASmutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis

Mohamed Bouchahda, Abdoulaye Karaboué, Raphaël Saffroy, Pasquale Innominato, Lee Gorden, Catherine Guettier, René Adam, Francis Lévi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 304 KB

english, 2010

11

Cetuximab and circadian chronomodulated chemotherapy as salvage treatment for metastatic colorectal cancer (mCRC): safety, efficacy and improved secondary surgical resectability

Francis Lévi, Abdoulaye Karaboué, Lee Gorden, Pasquale Fabio Innominato, Raphael Saffroy, Sylvie Giacchetti, Dominique Hauteville, Catherine Guettier, René Adam, Mohamed Bouchahda

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

12

May antioxidant therapy improve sperm parameters of men with persistent oligospermia after retrograde embolization for varicocele?

Giuseppe Paradiso Galatioto, Giovanni Luca Gravina, Giovanni Angelozzi, Antonia Sacchetti, Pier Ferdinando Innominato, Gianna Pace, Guido Ranieri, Carlo Vicentini

Journal:

World Journal of Urology

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

13

Feasibility of cetuximab given with a simplified schedule every 2

M. Bouchahda, T. Macarulla, G. LIedo, F. Lévi, M. E. Elez, B. Paule, A. Karaboué, P. Artru, J. Tabernero, D. Machover, P. Innominato, E. Goldschmidt, D. Bonnet, M. Ducreux, V. Castagne, R. Guimbaud

Journal:

Medical Oncology

Year:

2011

Language:

english

File:

PDF, 209 KB

english, 2011

14

The mechanism involved in the regulation of phospholipase Cγ1 activity in cell migration

Piccolo, Enza, Innominato, Pasquale F, Mariggio, Maria A, Maffucci, Tania, Iacobelli, Stefano, Falasca, Marco

Journal:

Year:

2002

Language:

english

File:

PDF, 888 KB

english, 2002

15

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway

Riley, Andrew M, Potter, Barry VL, Pandolfi, Pier Paolo, Broggini, Massimo, Iacobelli, Stefano, Innocenti, Paolo, Piccolo, Enza, Vignati, Sara, Maffucci, Tania, Innominato, Pasquale F

Journal:

Year:

2004

Language:

english

File:

PDF, 478 KB

english, 2004

16

90K (Mac-2 BP) and galectins in tumor progression and metastasis

Antonino Grassadonia, Nicola Tinari, Ida Iurisci, Enza Piccolo, Alba Cumashi, Pasquale Innominato, Maurizia D'Egidio, Clara Natoli, Mauro Piantelli, Stefano Iacobelli

Journal:

Glycoconjugate Journal

Year:

2002

Language:

english

File:

PDF, 187 KB

english, 2002

17

Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer

Pasquale F. Innominato, Sylvie Giacchetti, Georg A. Bjarnason, Christian Focan, Carlo Garufi, Bruno Coudert, Stefano Iacobelli, Marco Tampellini, Xavier Durando, Marie-Christine Mormont, Jim Waterhous

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 276 KB

english, 2012

18

Treatment with rituximab, dexamethasone, high-dose cytarabine, and oxaliplatin (R-DHAOx) produces a strong long-term antitumor effect in previously treated patients with follicular non-Hodgkin's lymphoma

D. Machover, B. Delmas-Marsalet, S.C. Misra, A. Ulusakarya, Y. Gumus, N. Frénoy, C. Guettier, R. Saffroy, P. Innominato, W. Almohamad, N. Brahimi, M. Haydar, E. Goldschmidt

Journal:

Biomedicine & Pharmacotherapy

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

19

Interrelations entre composantes physiologiques et moléculaires du système circadien de la souris

J. Beau, E. Filipski, P. Innominato, M.-W. Wu, X.-M. Li, F. Lévi

Journal:

Pathologie Biologie

Year:

2007

Language:

french

File:

PDF, 99 KB

french, 2007

20

Effects of light and food schedules on liver and tumor molecular clocks

E. Filipski, P.-F. Innominato, M.W. Wu, F. Lévi

Journal:

Pathologie Biologie

Year:

2007

Language:

french

File:

PDF, 59 KB

french, 2007

21

Importance du comportement circadien de l'hôte pour la genèse et l'évolution des cancers. Une revue

C. Focan, F. Lévi, P. Innominato

Journal:

Pathologie Biologie

Year:

2007

Language:

french

File:

PDF, 131 KB

french, 2007

22

Regulation of circadian rhythms and hypothalamic-pituitary-adrenal axis: an overlooked interaction in cancer

Pasquale F Innominato, Oxana Palesh, Firdaus S Dhabhar, Francis Lévi, David Spiegel

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

23

Skin surface temperature rhythms as potential circadian biomarkers for personalized chronotherapeutics in cancer patients

Scully, C. G., Karaboue, A., Liu, W.-M., Meyer, J., Innominato, P. F., Chon, K. H., Gorbach, A. M., Levi, F.

Journal:

Interface Focus

Year:

2011

Language:

english

File:

PDF, 1020 KB

english, 2011

24

The circadian rest-activity rhythm, a potential safety pharmacology endpoint of cancer chemotherapy

Ortiz-Tudela, Elisabet, Iurisci, Ida, Beau, Jacques, Karaboue, Abdoulaye, Moreau, Thierry, Rol, Maria Angeles, Madrid, Juan Antonio, Lévi, Francis, Innominato, Pasquale F.

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 438 KB

english, 2014

25

Circadian Disruption, Fatigue, and Anorexia Clustering in Advanced Cancer Patients: Implications for Innovative Therapeutic Approaches

Innominato, P. F., Mormont, M.-C., Rich, T. A., Waterhouse, J., Levi, F. A., Bjarnason, G. A.

Journal:

Integrative Cancer Therapies

Year:

2009

Language:

english

File:

PDF, 818 KB

english, 2009

26

Système circadien et symptômes associés au cancer

Innominato, P.F., Spiegel, D., Lévi, F.

Journal:

Médecine du Sommeil

Year:

2014

File:

PDF, 722 KB

2014

27

Impact of paroxetine on sleep problems in 426 cancer patients receiving chemotherapy: A trial from the University of Rochester Cancer Center Community Clinical Oncology Program

Palesh, Oxana G., Mustian, Karen M., Peppone, Luke J., Janelsins, Michelle, Sprod, Lisa K., Kesler, Shelli, Innominato, Pasquale F., Roth, Thomas, Manber, Rachel, Heckler, Charles, Fiscella, Kevin, Mo

Journal:

Year:

2012

Language:

english

File:

PDF, 236 KB

english, 2012

28

8706 Aggressive management of adult high risk patients with medulloblastoma (MB): 12 years experience at the Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru

Gallo, C. Saldaña, Innominato, P.F., Casavilca, S., Ayon, J., Valdivieso, N., Huaringa, M., Carracedo, C., Mas, L.

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

29

Wrist actimetry circadian rhythm as a robust predictor of colorectal cancer patients survival

Lévi, Francis, Dugué, Pierre-Antoine, Innominato, Pasquale, Karaboué, Abdoulaye, Dispersyn, Garance, Parganiha, Arti, Giacchetti, Sylvie, Moreau, Thierry, Focan, Christian, Waterhouse, Jim, Spiegel, D

Journal:

Chronobiology International

Year:

2014

Language:

english

File:

PDF, 419 KB

english, 2014

30

Prediction of Survival by Neutropenia According To Delivery Schedule of Oxaliplatin–5-Fluorouracil–Leucovorin for Metastatic Colorectal Cancer in a Randomized International Trial (EORTC 05963)

Innominato, Pasquale F., Giacchetti, Sylvie, Moreau, Thierry, Smaaland, Rune, Focan, Christian, Bjarnason, Georg A., Garufi, Carlo, Iacobelli, Stefano, Tampellini, Marco, Tumolo, Salvatore, Carvalho,

Journal:

Chronobiology International

Year:

2011

Language:

english

File:

PDF, 634 KB

english, 2011

31

Relief of Symptoms After Gefitinib Is Associated With Improvement of Rest/Activity Rhythm in Advanced Lung Cancer

Iurisci, I., Rich, T., Levi, F., Innominato, P. F., Tinari, N., Irtelli, L., De Tursi, M., Grassadonia, A., Iacobelli, S.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 228 KB

english, 2007

32

Fatigue and weight loss predict survival on circadian chemotherapy for metastatic colorectal cancer

Innominato, Pasquale F., Giacchetti, Sylvie, Moreau, Thierry, Bjarnason, Georg A., Smaaland, Rune, Focan, Christian, Garufi, Carlo, Iacobelli, Stefano, Tampellini, Marco, Tumolo, Salvatore, Carvalho,

Journal:

Year:

2013

Language:

english

File:

PDF, 562 KB

english, 2013

33

Subjective sleep and overall survival in chemotherapy-naïve patients with metastatic colorectal cancer

Innominato, Pasquale F., Spiegel, David, Ulusakarya, Ayhan, Giacchetti, Sylvie, Bjarnason, Georg A., Lévi, Francis, Palesh, Oxana

Journal:

Year:

2015

Language:

english

File:

PDF, 1.43 MB

english, 2015

34

Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?

Allard, M. A., Saffroy, R., de la Maisonneuve, P. Bouvet, Ricca, L., Bosselut, N., Hamelin, J., Lecorche, E., Bejarano, M. A., Innominato, P., Sebagh, M., Adam, R., Morère, J. F., Lemoine, A.

Journal:

Targeted Oncology

Year:

2015

Language:

english

File:

PDF, 229 KB

english, 2015

35

Sex moderates circadian chemotherapy effects on survival of patients with metastatic colorectal cancer: a meta-analysis

Giacchetti, S., Dugue, P. A., Innominato, P. F., Bjarnason, G. A., Focan, C., Garufi, C., Tumolo, S., Coudert, B., Iacobelli, S., Smaaland, R., Tampellini, M., Adam, R., Moreau, T., Levi, F.

Journal:

Annals of Oncology

Year:

2012

Language:

english

File:

PDF, 202 KB

english, 2012

36

ESMO 2014: new trends in precision medicine

Morere, J. F., Innominato, P.

Journal:

Targeted Oncology

Year:

2014

Language:

english

File:

PDF, 106 KB

english, 2014

37

Thoracic surface temperature rhythms as circadian biomarkers for cancer chronotherapy

Roche, Véronique Pasquale, Mohamad-Djafari, Ali, Innominato, Pasquale Fabio, Karaboué, Abdoulaye, Gorbach, Alexander, Lévi, Francis Albert

Journal:

Chronobiology International

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

38

Validation of Patient's Self-Reported Social Functioning As an Independent Prognostic Factor for Survival in Metastatic Colorectal Cancer Patients: Results of an International Study by the Chronotherapy Group of the European Organisation for Research and Treatment of Cancer

Efficace, F., Innominato, P. F., Bjarnason, G., Coens, C., Humblet, Y., Tumolo, S., Genet, D., Tampellini, M., Bottomley, A., Garufi, C., Focan, C., Giacchetti, S., Levi, F.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

39

Prevalence, putative mechanisms, and current management of sleep problems during chemotherapy for cancer

Palesh, Oxana, Peppone,, Innominato,, Janelsins,, Jeong, Monica, Sprod, Lisa, Savard,, Rotatori, Robert Maxwell, Telli,, Mustian,, Kesler,

Journal:

Nature and Science of Sleep

Year:

2012

Language:

english

File:

PDF, 337 KB

english, 2012

40

Circadian Rhythm in Rest and Activity: A Biological Correlate of Quality of Life and a Predictor of Survival in Patients with Metastatic Colorectal Cancer

Innominato, P. F., Focan, C., Gorlia, T., Moreau, T., Garufi, C., Waterhouse, J., Giacchetti, S., Coudert, B., Iacobelli, S., Genet, D., Tampellini, M., Chollet, P., Lentz, M.-A., Mormont, M.-C., Levi

Journal:

Cancer Research

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

41

The difference between in bed and out of bed activity as a behavioral marker of cancer patients: A comparative actigraphic study

Natale, Vincenzo, Innominato, Pasquale F., Boreggiani, Michele, Tonetti, Lorenzo, Filardi, Marco, Parganiha, Arti, Fabbri, Marco, Martoni, Monica, Lévi, Francis

Journal:

Chronobiology International

Year:

2015

Language:

english

File:

PDF, 180 KB

english, 2015

42

Nuisances sonores de l’environnement et sommeil du patient de réanimation

Elbaz, Maxime, Assefi, Mona, Sauvet, Fabien, Marin, Nathalie, Rio, Stéphane, Cariou, Alain, Innominato, Pasquale, Chennaoui, Mounir, Mira, Jean-Paul, Leger, Damien

Journal:

Médecine du Sommeil

Year:

2015

Language:

french

File:

PDF, 74 KB

french, 2015

43

Very late recurrence of Diethylstilbestrol - related clear cell carcinoma of the cervix: case report

Adani-Ifè, Ablavi, Goldschmidt, Emma, Innominato, Pasquale, Ulusakarya, Ayhan, Errihani, Hassan, Bertheau, Philippe, Morère, Jean François

Journal:

Gynecologic Oncology Research and Practice

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

44

Conversion to resection of liver metastases from colorectal cancer with hepatic artery infusion of combined chemotherapy and systemic cetuximab in multicenter trial OPTILIV

Levi, F. A., Boige, V., Hebbar, M., Smith, D., Lepere, C., Focan, C., Karaboue, A., Guimbaud, R., Carvalho, C., Tumolo, S., Innominato, P., Ajavon, Y., Truant, S., Castaing, D., De Baere, T., Kunstlin

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

45

Resectability after neoadjuvant FOLFIRINOX in locally advanced pancreatic cancer: A single-center experience

Pittau, G., Laurenzi, A., Innominato, P., Gelli, M., Ciacio, O., Allard, M.A., Cherqui, D., Castaing, D., Lewine, M., Adam, R., Sa Cunha, A.

Journal:

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

46

Relevance of internal time and circadian robustness for cancer patients

Ortiz-Tudela, Elisabet, Innominato, Pasquale F., Rol, Maria Angeles, Lévi, Francis, Madrid, Juan Antonio

Journal:

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

47

Use of Bevacizumab in the Management of Potentially Resectable Colorectal Liver Metastases: Safety, Pathologic Assessment and Benefit

Innominato, Pasquale F., Adam, René

Journal:

Current Colorectal Cancer Reports

Year:

2016

Language:

english

File:

PDF, 363 KB

english, 2016

48

Cross-talks between Circadian Timing System and Cell Division Cycle Determine Cancer Biology and Therapeutics

Lévi, F., Filipski, E., Iurisci, I., Li, X. M., Innominato, P.

Journal:

Cold Spring Harbor Symposia on Quantitative Biology

Year:

2007

Language:

english

File:

PDF, 371 KB

english, 2007

49

Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study

Lévi, Francis, Karaboué, Abdoulaye, Etienne-Grimaldi, Marie-Christine, Paintaud, Gilles, Focan, Christian, Innominato, Pasquale, Bouchahda, Mohamed, Milano, Gérard, Chatelut, Etienne

Journal:

Clinical Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

50

Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer

Bouchahda, Mohamed, Boige, Valérie, Smith, Denis, Karaboué, Abdoulaye, Ducreux, Michel, Hebbar, Mohamed, Lepère, Céline, Focan, Christian, Guimbaud, Rosine, Innominato, Pasquale, Awad, Sameh, Carvalho

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 953 KB

english, 2016

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